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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDKL3
All Species:
12.73
Human Site:
T413
Identified Species:
21.54
UniProt:
Q8IVW4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVW4
NP_001107047.1
592
67514
T413
P
N
P
I
N
P
S
T
N
C
N
G
L
K
E
Chimpanzee
Pan troglodytes
XP_517934
592
67566
T413
P
N
P
I
N
P
S
T
N
C
N
G
L
K
E
Rhesus Macaque
Macaca mulatta
XP_001108660
592
67612
T413
P
N
P
I
N
P
S
T
N
C
N
G
L
K
E
Dog
Lupus familis
XP_850612
456
51739
A301
K
F
I
P
E
L
R
A
K
L
L
Q
E
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLF2
595
67720
E415
T
N
P
L
N
P
S
E
N
S
D
G
V
K
E
Rat
Rattus norvegicus
Q9JM01
593
67534
A415
T
N
P
V
H
P
S
A
N
S
D
T
V
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512927
637
71445
I414
P
A
I
R
S
G
A
I
I
T
G
H
L
K
E
Chicken
Gallus gallus
P13863
303
34670
G148
V
I
K
L
A
D
F
G
L
A
R
A
F
G
I
Frog
Xenopus laevis
P35567
302
34487
F147
G
V
I
K
L
A
D
F
G
L
A
R
A
F
G
Zebra Danio
Brachydanio rerio
Q6AXJ9
350
40792
L195
V
G
C
V
F
A
E
L
L
S
G
A
P
L
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
I142
L
I
D
K
S
G
L
I
K
V
A
D
F
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784044
926
104004
H432
G
H
N
G
P
T
N
H
T
T
S
H
P
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
T139
N
L
L
I
D
R
R
T
N
A
L
K
L
A
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
T139
N
L
L
I
D
R
R
T
N
S
L
K
L
A
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
67.7
N.A.
80.5
79
N.A.
57.7
25
24.3
31
N.A.
23.4
N.A.
N.A.
30.2
Protein Similarity:
100
99.8
99.6
72.1
N.A.
89.7
87.6
N.A.
68.9
34.9
35.6
43
N.A.
35.1
N.A.
N.A.
44
P-Site Identity:
100
100
100
0
N.A.
60
46.6
N.A.
26.6
0
0
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
6.6
N.A.
80
73.3
N.A.
40
6.6
0
6.6
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
22.8
N.A.
23.1
N.A.
N.A.
Protein Similarity:
N.A.
33.9
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
15
8
15
0
15
15
15
8
22
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
22
0
0
0
0
0
% C
% Asp:
0
0
8
0
15
8
8
0
0
0
15
8
0
0
15
% D
% Glu:
0
0
0
0
8
0
8
8
0
0
0
0
8
0
43
% E
% Phe:
0
8
0
0
8
0
8
8
0
0
0
0
15
8
0
% F
% Gly:
15
8
0
8
0
15
0
8
8
0
15
29
0
15
15
% G
% His:
0
8
0
0
8
0
0
8
0
0
0
15
0
0
0
% H
% Ile:
0
15
22
36
0
0
0
15
8
0
0
0
0
0
8
% I
% Lys:
8
0
8
15
0
0
0
0
15
0
0
15
0
43
8
% K
% Leu:
8
15
15
15
8
8
8
8
15
15
22
0
43
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
36
8
0
29
0
8
0
50
0
22
0
0
0
0
% N
% Pro:
29
0
36
8
8
36
0
0
0
0
0
0
15
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
8
0
15
22
0
0
0
8
8
0
0
0
% R
% Ser:
0
0
0
0
15
0
36
0
0
29
8
0
0
8
0
% S
% Thr:
15
0
0
0
0
8
0
36
8
15
0
8
0
0
0
% T
% Val:
15
8
0
15
0
0
0
0
0
8
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _